Ursodiol
Ursodiol questions and answers
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Q: Ursodiol or Actigall for guinea pig bladder stone?
I'm wondering if anyone has heard of using Ursodiol or Actigall for guinea pigs to break down bladder stones? My vet only told us about surgery, but I don't think my pig would make it through and I want to try anything else that might work before putting her through that. I'd also like to see if anyone else's pig has been prescribed this before I go asking my vet about it. Thanks!
A: Diagnosis and Treatment:
An x-ray or ultrasound will identify stones. An experienced veterinarian can remove bladder stones surgically. Occasionally a guinea pig may be able to pass a stone before surgery so it may be a wise precaution to perform an X-ray immediately before any surgery to locate the stone.
Sometimes stones can be flushed or plucked from a sow's urethra. Several weeks of an antibiotic like bactrim will prevent infection while the bladder is healing. The article on post operative care lists tips to aid recovery.
Prevention:
The cause of bladder stone formation is poorly understood. Because stones seem to run in families, it is likely there is a strong genetic component. Frequent urinary tract infections have also been implicated. A good quality diet is thought to help prevent the formation and reformation of bladder stones. For an explanation of the calcium:phosophorus ratio and diet and a discussion explaining how Polycitra can help prevent the reformation of some types of stones, see: Ca:P & Polycitra
Q: should you drink alot of grapefruit juice while taking ursodiol?
A: That would be a good question to ask your doctor, not us, the nice people on YA.
Q: can i take phentermine/adipex if im on ursodiol?
A: Call your pharmacist. Its their job to look up all of your medications and ensure they won't be any reactions. Don't worry, they don't see it as a bother, they're just as concerned about keeping you healthy as your doctor is. (Plus, they're concerned about lawsuits, since if they dispense both and you get sick, their asses can go on the line too.)
Q: need information on medicine Ursodiol usp 150mg?
A: Ursodiol is a bile acid that decreases the amount of cholesterol produced by the liver and absorbed by the intestines. Ursodiol helps break down cholesterol that has formed into stones in the gallbladder. Ursodiol also increases bile flow in patients with primary biliary cirrhosis.
Ursodiol is used to treat small gallstones in people who cannot have gallbladder surgery, and to prevent gallstones in overweight patients undergoing rapid weight loss. Ursodiol is also used to treat primary biliary cirrhosis.
Ursodiol is not for treating gallstones that are calcified.
Q: To Vets and Vet Techs..... My cats was diagnosed with accute liver failure and was placed on Ursodiol?
He was also placed on Denosyl and Flagyl... This was all about 2 months ago, he is still not doing better- he is actually getting worse now he is also anemic. I stopped giving him the Flagyl the taste is so bad for him, he throws it up immeditalty and refuses to eat (so we have to force feed him through a syringe, which is also not easy)..... I recently read that the ursodiol is generally perscribed to help with gallstones and can cause him nasuea. Is this medication actually bad for his liver? The only article I found on it was in very Technical terms that I didn't understand. PLEASE help- I don't know whether to trust my vet or not I would like more info before making the decsion to switch vets (I don't exactly have the money at the moment to take him to multiple vets)... My cat is almost to the point where I may have to put him down and he is only about 3- if I had the money I wouldn't care how much it would cost to keep him alive but i just don't have the resources right now.
A: Sometimes it is more humane to just go ahead and put them down. I understand not wanting to, believe me, but put yourself in his place. What would you want? Is he living a quality life - will he ever be able to? Find a vet that will finance the cost. Call your local humane society and ask them what you should do. They are very knowledgeable about animals - obviously.
Q: Are there any preemie Day cares out there?
My son was born September 27th, 2006 @ 26wks. His health is great except for these tiny galstones that he has. He has to take this medicine called Ursodiol twice a day. It gets very nerve racking but I know he needs it. My question is: Does anyone know of any daycares for premature babies or have you ever heard of a such thing? I'm asking because I would really like to go back to work or school. The only thing stopping me is daycare for my son. I want him somewhere that I know will be able to handle his condition and will make sure he has his meds and also, is skilled enough to care for premature children. Please help me. I dont know if I should just stay home until he turns one or continue to search for a daycare. I NEED him in a safe place, so that when I am at work or school I will know he is well taken care of.
A: I am the mom of a preemie (dd was born at 35 weeks). I found that the best thing we did was find an in home daycare provider. Someone who does child care out of their home. That way they can give the meds on time and correctly. The problem with private daycares or public for that matter. You have different people working on different days. And they might not know that your son would need the medicine at a certain time. We looked into putting out dd into La Petite Academy and they told me they couldn't guarantee that they could give the meds on time. I didn't think that was acceptable. So I went to our local daycare association and got a list of local in home providers. We interviewed 12 providers. We decided on 3 to do background checks and references. We asked for 3 current clients and 3 past clients. Our daughter actually excelled in the in home daycare! She is speech delayed and had sensory issues. But with the one on one contact with the daycare provider it actually helped her catch up with the other children her own adjusted age.
Q: Any pharmacists or Doctors Please!! Very Important!!?
well my doctor gave me pills to take for my stomach attacks wich is called URSODIOL 300MG, and said that im not suppose to take any other pills with that such as pain killers and etc. Well I just took the Plan B pill...would plan b still work or what? Will it effect it?
A: http://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a699047.html
try this site.
Plan B will still work... and you may wish to take another dose of Plan B. And as well, you can skip a dose of Ursodiol and nothing will really happen, since it is an anticholesterol and anti gall stone med. It is far more important that you use plan B than you take this med ever single instant of your life. The gall stones will still be there next week... Plan B won't work next week.
Q: My cat is sick...not sure what to do or think, please read and help if you can.?
My cat is a 16 month old pure breed maine coon male. He is the second male cat, and third cat that we got from the same breeder. The previous male cat had to be put down due to suspected FIP. Our current male cat is now exhibiting the following symptoms:lethargy, some vomitting,mild weight loss,constipation, abnormal liver values (as far as the abnormal values, i'm not sure which ones are abnormal..i think it was low BUN, and some others). On the bright side my cat still has an appetite and eats, drinks and uses the bathroom regularily, he still loves attention, although not as much as he used to. He is now taking Ursodiol, and Denosyl daily and will have is blood rechecked in 4 weeks. I'm trying to convinve myself that its not FIP again, but I am losing hope. Does anyone have any silver lining ideas as to what else he may have? The vet wanted to do further bile testing, and I don't mind except that if my cat is dying I don't want to put him through testing that will eventually have the same prognosis:death, it just seems pointless to me. While I don't want him to die, I also don't see the point of spending hundreds if not thousands of dollars on tests if the end result will be the same. Does anyone have any words of wisdom for me? thanks, andrea
A: Gawd, did the breeder check her cats for FIP? Two from the same breeder with this problem is not ethical.
There is a VERY good FIP cat list over on Yahoogroups as well as people on the Handicats group over there as well who can advise you. I'd say it'd be a really good thing to go check them out and join, the owners there have had cats with this and can give you as much feedback as you need.
I really hope your cat doesn't have FIP, it may be something else. It doesn't sound like FIV (that's only a fever and the BUN levels, for short term, then the cat bounces back), and it doesn't sound like FeLV either.
Q: Any veterinarians on here? Need advice! IG with liver problems?
My five year old Italian Greyhound, Sable, began acting strangely last weekend. I took her to her vet on Monday, and she was found to have elevated liver enzymes. A bile acids test the next day showed levels twice as high as they should be.
I've taken Sable to the vet everyday this week for IV fluids. Even with this, beginning to eat again, eating prescription dog food, and receiving medications (Amoxi, Vit E, Denamarin, Ursodiol and Lactulose) her labs have gotten worse.
Does anyone have any further advice? Does this regimen seem appropriate? Any assistance would be much appreciated. This is my little girl!
Note: The vets believe this issue was caused by being put on Phenobarbital and eating sugerfree gum with Xylitol.
A: I would talk with your vet about getting an ultrasound/biopsy (only after a coagulation profile is run). That will show the cell response. You can also have a Copper measurement done to see if that is high and contributing to the problem. Another medication that may help is Metronidazole (flagyl), but it has to be dosed at the lower "liver" dose (7mg/kg). Is your dog eating anything? What are the kidney values? Has leptospirosis been ruled out? Have they checked the protein levels? Your dog, due to the decreased production of protein by the liver and due to dilution due to fluid administration, may be low.
The other thing that I would suggest is to have your dog get IV fluids at the emergency vet over night. That way, treatment can continue. IV fluids only stay in the bloodstream for about 40 minutes after they are given. So, if your vet unhooks them at 5 PM, by 6 PM none of the fluids given are still there. Fluids overnight may greatly improve the chance of survival.
Q: Would Dr Frank or anyone answer my fatty liver disease question?
I had been to many doctors until I self-taught myself to identify the various nutritional triggers to the pruritus Urticaria I was being troubled with for over a year. I am doing much better but my nutritional triggers are so miniscule that I think I either have very severe non-alcoholic fatty liver disease or possibly PSC or PBC.
MY QUESTION IS: what therapies are there for PBC or PSC besides (1) ursodiol bear bile, and (2) also better and better micro-nutritional ‘adjustments,’ or (3) a whole liver transplant?
Thanks so much for any answers or ideas.
AI – a self taught nutritionIsT ><+>[(-:]
My symptoms are many many triggers that cause blistering pruritus with a fever in my thighs which occurs within minutes or hours after I eat or apply a trigger to my skin.
My worst trigger is organic olive oil which begins to itch in 5 to 20 minutes after application.
Another is when I eat over 150 calories of almonds or sesame seeds which will cause blisters and pruritus and a thigh fever in three hours.
A high carb 800 calorie meal will trigger blisters and pruritus and a thigh fever in 3 to 4 hours.
These are very consistent trigger responses which I have read is very similar to those with fatty liver disease. Obesity is oftentimes associated with both alcoholic and non alcoholic liver disease, but many people who have this liver disease are not obese, since I apparently have it in spades.
It is a most miserable condition.
I sincerely thank those who are like Dr. Frank and would respond intelligently with your insights.
My best to all.
AI – self nutritionIsT ><+>[(-:]
Thank you Renata for your response.
I hope a good specialist will eventually answer my question(s) since I am looking for more hope from my continual sufferings with pruritus/rash flareups. There are very few specialists in this area unless one's insurance is very very good.
Sooo MY QUESTION IS: what therapies are there for PBC or PSC besides (1) ursodiol bear bile or (2) a whole liver transplant or (3) better and better micro-nutritional ‘adjustments’ to minimize the triggers whenever they show up and to 'perhaps' heal the root problem(s) of a weakened liver?
Also, rather than allowing my disease to progress to requiring a full liver transplant, are stints oftentimes uses to open up clogged biliary glands? I have read that is rarely an option for some reason and a liver transplant will be out of the question with my age/income/insurance-provider.
Thanks anyone.
AI – self nutritionIsT ><+>[(-:]
Dr. Frank,
Thank you so much for passing on what you felt was correct for my situation. We are all learning from each other in this struggle for better health and ultimately the struggle for humankind to survive the inadequate information that we are all inundated with on a daily basis.
We both readily agree that my prior poor micro-nutrition was the cause of my present problems; soo I will continue to do my nutritional research and adjust my micro-nutrition absorption since this appears to be the only choice I might ever have.
Thank you again for passing on your insights.
I pray you will continue your good work forever with health and peace.
AI
A: I am very much afraid your diagnoses,conclusions and proposed managements are all pretty illogical from start to finish.
Food allergies are a bit of a minefield and there influences on symptoms and disease are uncommon and vastly over-reported, fed by a healthy pseudo-scientific industry based on disreputable and facetious allergy testing.
Fatty liver is directly caused by obesity, the body basically running out of places to stuff spare fat, and its management is basically weight loss.
Primary Sclerosing Cholangitis requires specialist investigation to confirm the diagnosis and the majority of patients have a history of chronic ulcerative colitis. Primary Biliary Cirrhosis is an easy diagnosis to confirm or refute as most patients have anti-mitochondrial antibody.
It is said of doctors 'the doctor who treats himself has a fool for a patient.' I am afraid this is doubly true of the amateur.